Our Approach
Design Controls & Risk Management: An Integrated Product Development Approach
Day One
1) Introduction
- Instructor and Class Introductions
- Course Objectives & Expectations
- Review Participant Objectives
2) Overview of Design Controls
- What is Design Control? (Concepts Defined)
- Why is Design Control important?
- FDA’s Cradle to Grave Vision of the Total Product Life Cycle
- The “Unwritten Laws” of Design Control (Planning, Documentation, Risk Based Approach, Interactions)
3) Phase 0 (Research)
- Timing of Design Control Elements During Product Development
- When Does Design Controls Start? When Does It End?
- Concept & Feasibility
- Development phases overview (phase 0-V)
4) Phase I (Requirements & Planning)
- Design and Development Planning
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- Why does FDA require planning?
- Developing Practical Design and Development Plans
- Topics Addressed in DDP
- User Needs & Marketing Inputs
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- What Are User Needs?
- Characteristics of Effective User Needs
- Identifying User Needs
- User Needs vs. Marketing Inputs
- Review User Needs
- Workshop Exercise: Developing User Needs
(Group Break Out)
- Design Input Development
- What Are Design Inputs?
- Characteristics of Design Inputs
- Purpose of Design Inputs
- Design Inputs vs. User Needs
- Intended Use
- The Process of Developing Effective Design Inputs
- Design Inputs & Human Factors
- Review Design Inputs
- Workshop Exercise: Develop Design Inputs (Group Break Out)
Risk Management Planning
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- How to perform risk planning
- Examples
Lunch
5) Phase II
- Preliminary Design
- Preliminary Hazard Analysis
- What is a Preliminary Hazard Analysis and why is it important?
- Elements of a Preliminary Hazard Analysis
- Preliminary Hazard Analysis Exercise
- Detail Design and Development / Testing
- Risk Assessment
- Hazard Analysis
- Risk Analysis
- Risk Evaluation
- Workshop Exercise: Performing a Risk Assessment
(Group Break Out)
- Risk Mitigation and Control
- Identifying Risk Controls and Implementation
- Workshop Exercise: Implementing Risk Controls
(Group Break Out)
- Design Reviews
- Purpose of Design Reviews
- Reviewer Roles
- Documenting Design Reviews
- Formal vs. Informal Reviews
- Types of Design Reviews
- Characteristics of Effective Design Reviews
- Practical Implementation and Best Practices
Day Two
- Design Output
- What are Design Outputs? What are Essential Design Outputs?
- Effectively Documenting Design Outputs
- What is the Device Master Record?
- Exercise: Identifying Design Outputs
- Design Verification
- Purpose of Design Verification
- Types of Verification
- Verification Planning
- Documenting Verification: Protocol and Report Designs
- Practical Implementation and Best Practices
- Workshop Exercise: Effectively Plan and Execute Verification
(Group Break Out)
Design Transfer Planning & Initial Design Transfer Activities (Phase I&II)
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- Purpose of Design Transfer
- Three Key Components of Effective Design Transfer Procedures
- Documenting Design Transfer Activities and Deliverables
- Design Transfer: It's a Process, Not an Event!
- The Design Transfer Process: Planning, Execution, Qualification
- The Design Transfer Team and Design Transfer Reviews
- Practical Implementation and Best Practices
6) Phase III (Design Transfer)
- Final Design Transfer / Final Execution (Phase 3)
Lunch
7) Phase IV
- Design Validation
- Purpose of Design Validation
- What Is Design Validation?
- Validation vs. Verification (What's the difference?)
- Types of Validation
- Is Process Validation a Part of Design Validation?
- Validation Planning & Human Factors: A Risk Based Approach
- Documenting Validations: Protocol and Report Designs
- Practical Implementation and Best Practices
- Workshop Exercise: Design Validation (Group Break Out)
Final Risk Assessment Verification: Effectiveness
- Risk Management Report
- What is included in a risk management report?
- Risk Management: Production and Post-Production Information
- Implementing a production and post-post production feedback process
8) Phase V
- Regulatory Submission & Approval
- Commercialization & Product Launch
9) Design History File
- Purpose of the Design History File
- Contents of a Design History File and Record
- DHF vs. DMR vs. DHR
- DHF vs. Technical File vs. 510k
10) Design Change
- Purpose of Design Change
- Document Control vs. Change Control
- When Should Design Change Begin?
- Design Change Process (Development vs. Production)
- Elements of Effective Design Change
- Practical Implementation, Best Practices, and Examples
11) Question and Answer Session / Course Evaluation